Gallstones: Volume 139 : Pathogenesis and Treatment download pdf
Gallstones: Volume 139 : Pathogenesis and Treatment download pdf

Gallstones: Volume 139 : Pathogenesis and Treatment by G. Alder
Gallstones: Volume 139 : Pathogenesis and Treatment
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Author: G. Alder
Number of Pages: 259 pages
Published Date: 16 Oct 2004
Publisher: Kluwer Academic Publishers
Publication Country: United States
Language: English
Type: Pdf
ISBN: 9780792387985
File size: 8 Mb
Download Link: gallstones volume 139 pathogenesis and treatment
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This book, the proceedings of the Falk Syposium No. 139 on 'Gallstones: Pathogenesis and Treatment', held in Freiburg, Germany, on January 15-16, 2004, reflects the tremendous advances in the field of biliary diseases both at the genetic and cellular as well as the clinical levels. In industrialized countries, gallstones are a frequent clinical entity with a prevalence of 10-15%. In clinical practice one can differentiate between cholesterol stones, black pigment stones and brown pigment stones. 80-90% of gallbladder stones are cholesterol stones, 10-20% are black pigment stones. The prevalence of cholesterol stones increases with age and in Europe in the 70-plus age group reaches about 20% in males and about 30% in females. Gallstones and gallstone diseases, therefore, are a frequent and important clinical problem. This book addresses the basic aspects of gallstone pathogenesis as well as the non-surgical and surgical treatment of gallstone diseases.Of particular interest are the epidemiology and genetics of gallstone formation, with definition of risk factors, in particular of genetic predispositions. Other major aspects are the hepatocellular and bilary transport mechanisms that predispose to the formation of gallstones. Apart from cholesterol and lipid transport and absorption, gallbladder function plays a central role in gallstone formation. Another clinically very relevant topic is the treatment of gallstone diseases by drugs, endoscopic and other non-surgical interventions, and surgery, as well as the long-term outcome of therapeutic interventions. This volume concludes with a state-of-the-art chapter on 'Gallstone Research in the Post-Genomic Era'."Gallstones: Pathogenesis and Treatment" is an excellent update on the pathogenesis of gallstones as well as on the treatment of gallstone diseases, written by an international faculty of outstanding clinicians and scientists. This book will, therefore, be of great interest to hepatologists and gastroenterologists in academic institutions as well as in clinical practice.

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